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Dr rosenberg half life8/25/2023 We have monitored for the first time translational dynamics during the developmental process of sporulation within the two distinct cellular compartments of forespore and mother-cell. Further, the variability pattern of translational activity varied among the cells, being affected by nutrient availability. By comprehensive monitoring the activity of the major rrn promoters and ribosomal protein production, we revealed diverse dynamics between cells grown in rich and poor medium, with the most prominent dissimilarities exhibited during deep stationary phase. subtilis) as a model organism, we followed the dynamics of the translational machinery at a single cell resolution during growth and differentiation. The ability of bacteria to responsively regulate the expression of translation components is crucial for rapid adaptation to fluctuating environments.
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